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Buy Lophophora Williamsii (Peyote)


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The active alkaloids of the Peyote cactus are:
* mescaline (3,4,5- trimethoxy-B-phenethylamine)
* n-methylmescaline
* n-acetylmescaline
* lophophorine
* thyramine
* hordinenine
* anhalaninine
* anhalonidine
* pellotine
* o-methyllanhalonidine

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 Buy Lophophora williamsii (Peyote)

Lophophora williamsii (peyote) – The peyote, scientific name Lophophora williamsii , is a small, spineless cactus with psychoactive alkaloids, particularly mescaline. Peyote is a Spanish word derived from the Nahuatl peyōtl [ˈpejoːt͡ɬ], meaning “caterpillar cocoon”, from a root peyōni, “to glisten”. Peyote is native to Mexico and southwestern Texas. It is found primarily in the Sierra Madre Occidental, the Chihuahuan Desert and in the states of Nayarit, Coahuila, Nuevo León, Tamaulipas, and San Luis Potosí among scrub. It flowers from March to May, and sometimes as late as September. The flowers are pink, with thigmotactic anthers (like Opuntia). Lophophora williamsii for sale

Known for its psychoactive properties when ingested, peyote is used worldwide, having a long history of ritualistic and medicinal use by indigenous North Americans. Peyote contains the hallucinogen mescaline

Lophophora williamsii (peyote), is a species of cactus that contains the psychedelic chemical mescaline. It has a distinctively small, green, and globular appearance, growing close to the ground without any spines. These “crowns” or “buttons” are traditionally cut from the root of the peyote plant and dried for ceremonial use.

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Native to Mexico and the Southwestern US, peyote has long been a focus of Native American and pre-Colombian ceremonial traditions. Its name derives from the Nahuatl (Aztec) term peyotl and it remains legal for ceremonial use in the US under the American Indian Religious Freedom Act. Today, it’s also used in other contexts elsewhere, including in meditation and psychotherapy. It also holds the reputation of being the first psychedelic to come to mainstream Western attention—for better or worse. Due to overharvesting and peyote’s slow-growing nature, the cactus is now an endangered species.

In ceremonial use, peyote is typically either chewed to release the active alkaloids or brewed as a tea. The peyote trip is characterized by visual effects (such as enhanced colors and breathing environments), philosophical and introspective insights, and feelings of euphoria.

What to expect

The effects of peyote are usually felt within 30 minutes to an hour after consumption. For most, the experience begins with some form of physiological discomfort, such as nausea, fullness in the stomach, sweating, and/or chills. These physical symptoms can last up to two hours, before dissolving into a sense of calm and acceptance. At this point, the more subjective, psychological effects take hold, reaching their peak two to four hours after consuming the cactus and gradually declining over the next eight to twelve hours. Peak effects are compared to those of LSD, and are known to profoundly alter one’s perceptions of self and reality, increase suggestibility, and intensify emotions. While some find peyote more sensual and less reality-shifting than LSD, others have trouble telling the difference.

Some people experience a deeply mystical or transcendental state, including clear and connected thought, feelings of oneness and unity, self-realization, and ego death, as well as empathy and euphoria. “Bad trips” and dysphoric symptoms tend to be more common among people who ignore the importance of set and setting and/or have a history of mental illness.

Visual effects are also common, including color enhancement, visual distortions (such as “melting” or “breathing” environments), geometric patterns, and the appearance of seemingly autonomous entities. A number of users, including the writer Robert Anton Wilson in his autobiographical book Cosmic Trigger, describe encounters with a little green man, or the “spirit of the plant,” who is often called “Mescalito.”

Lophophora williamsii (peyote) Pharmacology

Something of a “little green chemical factory,” peyote contains more than 60 different alkaloids, many of which are at least potentially psychoactive to varying degrees, including tyramine, hordenine, pellotine, and anhalonidine.[5] But the primary psychoactive alkaloid is mescaline.

Receptor binding

Mescaline binds to virtually all serotonin receptors in the brain but has a stronger affinity for the 1A and 2A/B/C receptors. It’s structurally similar to LSD and often used as a benchmark when comparing psychedelics.

Like nearly all psychedelics, the effects of mescaline are likely due to its action on serotonin 2A receptors.

Lophophora williamsii (peyote) Dosage

A light dose of peyote is 50-100g fresh or 10-20g dry, which equates in either case to roughly three to six mid-sized buttons. Moderate doses range up to 150g fresh or 30g dry (six to twelve buttons), while strong doses range up to 200g fresh or 40g dry (eight to sixteen buttons). Anything above this is considered heavy.

It is hard to be precise, however, due to the varying levels of mescaline in any given peyote button. Growing location and season of harvest can also affect their potency, as can age—older peyote tends to be more potent.

The effects of the Mescaline Peyote cactus

The effects of this small bulb cannot be called recreational and therefore we recommend only use this cactus in a familiar quiet environment, such as your living room. We also always recommend inviting a trip sitter if you are planning a wonderful spiritual journey with Mescaline as your vehicle. A trip sitter is a sober person who can assist you during the trip. Peyote has a strong antibacterial effect and can even kill bacteria that are resistant to penicillins. The Mescaline in Peyote is very potent hallucinogen and will provide you with lifelike hallucinations and visions during the trip. Mescaline Peyote is definitely not a party or social psychedelic. The Peyote is a true transformer of body and mind and is mainly intended for spiritual self-development and / or for detecting or remedying illnesses and ailments. Any side effects of a trip on Mescaline Peyote can include cramps, nausea, vomiting and crying. These symptoms disappear within about an hour when the trip starts.

  • Changes in perception
  • Increase in problem-solving thinking
  • High self-reflection of character, ego
  • Lifelike hallucinations and visions
  • Increase in sensory sensitivity
  • Distortion of objects
  • Manifestation of the light in every person or object visible
  • Changing mood, laughing, crying, sad, happy


Peyote Mescaline and the brain

Mescaline is a psychedelic alkaloid found in nature. The Mescaline alkaloid is very similar to the body’s neurotransmitter epinephrine (adrenaline). Because of this similarity, the psychedelic chemical compound of Mescaline can bind to serotonin and dopamine receptors in the brain. This binding process causes psychedelic and hallucinatory effects. In addition to Mescaline, there are many other substances in the Peyote cactus that play a somewhat smaller but also active role after ingestion of the Peyote cactus.

How do I use Mescaline Peyote cactus

Of course you cannot consume Peyote cactus immediately upon arrival. The Peyote will have to be processed and dried before it is ready for consumption. Cut the Peyote into small pieces and let it dry well. Once dry grind the pieces into a fine powder. The Peyote is now ready for consumption. The powder can be encapsulated, chewed or swallowed. For a 1 person trip you need about 27 grams (300mg Mescaline) of dried Peyote.

Dosage of dried Mescaline Peyote

14 – 27 grams (150 – 300mg Mescaline) light to medium dose
27 – 36 grams (300 – 400mg Mescaline) strong trip, duration: 6 to 12 hours
40 – 45 grams (450 – 500mg Mescaline) extreme trip, possible ego dissolution, duration: + / – 12 hours
45 – 55 grams (500 – 600mg Mescaline) guaranteed dissolution of the ego, duration: +/- 24 hours


Research into the harm potential of peyote is limited, but in general, it is considered a safe substance. A lethal dose has never been identified, probably because it’s too high to be taken accidentally. In other words, to the best of our knowledge, nobody has ever died from a peyote overdose.

A 2005 study into the ceremonial use of peyote among Native American populations found no detrimental long-term effects. It should be noted, though, that its use in other contexts may not be as safe—later studies have found an association between prior mental health problems and “bad trips.” Still, peyote appears to present little risk of flashbacks, or hallucinogen persisting perception disorder (HPPD).

Peyote is traditionally consumed by Huichol women during pregnancy, but mescaline has been linked to fetal abnormalities and should be avoided by pregnant or breastfeeding women.

It should also be avoided by anyone with a heart condition and/or high blood pressure, particularly in combination with blood pressure medications. Other drugs to avoid combining with peyote include tramadol, immunomodulators, alcohol, and stimulants like cocaine and amphetamines. Combining peyote with monoamine oxidase inhibitors (MAOIs) could increase nausea and may even be dangerous. In fact, the nausea that tends to arise from taking peyote alone may have something to do with the presence of naturally occurring MAOIs.

THERAPEUTIC USE of Lophophora williamsii (peyote)

In the Native American Church, peyote ceremonies are often used to treat drug and alcohol addiction. And, tellingly, while alcoholism (or at least alcohol abuse) among the Navajo and other Native American tribes is often said to be more than twice the national US average, it tends to be especially low among members of the Native American Church. Whether peyote (or mescaline) therefore represents a promising therapy for alcohol addiction is up for debate, but these findings are supported by anecdotal reports as well as studies into the therapeutic benefits of other psychedelics. Indeed, even William “Bill W” Wilson, the founder of Alcoholics Anonymous, was in favor of psychedelic intervention.

Peyote’s effect on the serotonin system likely has something to do with the treatment of substance addiction, but the set/setting and social support inherent in the traditional ceremony may have just as much if not more of a therapeutic effect. In addition to the sacrament of peyote, for instance, these ceremonies feature a master guide, marathon group sessions, ego reduction techniques, social networks, and a focus on self-actualization throughout.

As a traditional addiction therapy, the peyote ceremony can also provide an addict with visions of his or her eventual ruin, effectively simulating what alcoholics refer to as “rock bottom” and sparking a very real sense of urgency to change. The trance-like state of a ceremony’s continuous drumming and chants can also increase self-awareness, break down denial mechanisms, and give addicts a sense of control.

In addition to its direct effects on the serotonin system, peyote is also associated with a strong “afterglow” effect that can last for up to 6 weeks after a ceremony. During this period, users commonly report feeling happier, more empathic, less prone to cravings, and more open to communication—all of which is likely to boost the efficiency of follow-up therapy sessions. Of course, this has obvious implications for the treatment of depression as well, especially given that depression scores are reportedly lower among more active members of the Native American Church.

In fact, studies suggest that mescaline may increase blood flow and activity in the prefrontal cortex, the area of the brain in charge of planning, problem-solving, emotional regulation, and behavior. Low activity in this area is linked to depression and anxiety, leading scientists to hypothesize that mescaline could help alleviate symptoms of these disorders.

Mescaline could also help reduce suicidal thoughts, according to researchers at the University of Alabama. Using data from the National Survey on Drug Use and Health, the researchers found that people who have used a psychedelic drug at least once in their life show lower rates of suicidal thinking.

A 2013 study also found that lifetime mescaline or peyote use was significantly linked to a lower rate of agoraphobia, an anxiety disorder where subjects perceive their surrounding environment to be threatening.

Legality of peyote in the United States

In the United States, despite it being a federally controlled Schedule I substance—even in its natural state—peyote is legal for members of the Native American Church under the American Indian Religious Freedom Act. And even non-Indians may be permitted to use it as part of “bona fide” ceremonies or serious research.

Peyote can also be consumed with relative freedom—regardless of religious affiliation—in the City of Oakland, CA, which decriminalized all “entheogenic plants” containing indoleamines, tryptamines, or phenethylamines, making it legal for adults aged 21 and over to consume peyote and other plant medicines—regardless of ethnicity and religious affiliation. It also specifically decriminalizes (or rather deprioritizes for law enforcement) their cultivation and distribution.

Legality of peyote in Mexico

Peyote is also a Schedule I substance in Mexico, where harvesting the plant from the wild is controlled due to peyote’s endangered status. Again, however, religious use is permitted.

Legality of peyote in Canada

In Canada, although extracted mescaline is illegal, fresh (not dried) peyote and other mescaline-containing cacti are specifically exempt from scheduling.

Legality of peyote in the UK and elsewhere

The situation is much the same in the UK (even after the Psychoactive Substances Act) and elsewhere in Europe, where it tends to be legal to grow peyote but not to prepare it for use.

In Australia, the legality of peyote varies by state. For example, it is illegal in Western Australia, Queensland, and the Northern Territory, but legal to grow (as long as it’s not for use) in Victoria and New South Wales, among other states.

Current usage

According to the Global Drug Survey in 2014, mescaline or peyote were only among the top 20 drugs for past month usage in Mexico. Peyote was taken by 6.4% and mescaline by 4.4% of 643 Mexican survey respondents.

Of course, we cannot generalize current usage statistics from such limited data, but it does give us some idea of its popularity relative to other substances. Unfortunately, precise usage statistics for peyote aren’t really available because surveys tend to lump it together with other substances like LSDpsilocybin, and MDMA. Hence, SAMHSA’s 2014 finding that 0.4% of the US population used “hallucinogens” in the past month is more or less meaningless.

That said, we can trace the popularity of peyote over time by looking at its appearance in publications and Google searches. The number of publications related to peyote and mescaline peaked in the 1940s and 50s, followed by a much larger spike in the 1960s and 70s—during the psychedelic revolution and roughly coinciding with the publication of Carlos Castaneda’s books. Interest spiked again in the 1990s, presumably due to the Mexican government’s 1991 listing of peyote as an endangered species and the 1994 amendments to the American Indian Religious Freedom Act. Published mentions steadily decreased over the next decade or so, possibly because of the rising popularity of other psychedelics like LSD and psilocybin.

Google searches, meanwhile, have remained fairly steady for peyote since 2004—although searches for mescaline have decreased. Searches for peyote did reach an all-time high in December 2014 (and again in May 2015) but this was most likely in relation to its appearance in the video game Grand Theft Auto V. Unsurprisingly, most Google searches for peyote come from Mexico, the United States, and Canada. (The popularity of the search term in Uruguay likely has more to do with the Uruguayan band El Peyote Asesino.)

Where does peyote grow?

The peyote cactus grows primarily in Mexico—in the Chihuahuan Desert and the scrublands of Coahuila, Nuevo León, Tamaulipas, and San Luis Potosí. It also grows in the American Southwest. You can often find peyote in Texas and New Mexico, for instance.

The map below shows a rough outline of traditional peyote locations. For ceremonial practitioners, this has long been the grounds where peyote is collected in the wild.

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Peyote plant locations have shifted and diminished over time, though. In some regions where the cactus once thrived, there may now be none whatsoever.

“There are two species or types of peyote”

Some Native American tribes identify two species or types of peyote, which the Huichol call Tzinouritehua-hikuri (Peyote of the God) and Rhaitoumuanitari-hikuri (Peyote of the Goddess) in reference to their differing size, potency, and palatability. Botanists, however, recognize only one species of peyote: Lophophora williamsii. This is the peyote Native American tribes have venerated for millennia. The superficial differences are instead attributed to other factors, such as age.

There is another species in the Lophophora genus, the Lophophora diffusa, that looks remarkably like peyote, but it contains only trace amounts of mescaline—and sometimes none whatsoever. Instead, this so-called “false peyote” contains high levels of the narcotic alkaloid pellotine.

“Peyote is legal in the United States”

The legal status of peyote in the US can be confusing, but by and large, the consumption of peyote is illegal—it is, after all, a Schedule I substance. However, peyote is legal for members of the Native American Church under the American Indian Religious Freedom Act. Non-Indians may be permitted to use it as part of “bona fide” ceremonies or serious research, and in the City of Oakland, its use has been decriminalized, but it is not legal in the true sense of the word.

Can it be detected in a drug test?

Mescaline can be detected in the urine for one to four days after use, but it’s not included in either standard or extended drug screens. Virtually all labs require a specific test for the substance, so unless your employer is a real stickler and worried that you’ve been spending your free time at peyote ceremonies, you should be fine.

Is peyote illegal unless you’re in the Native American Church?

It depends on your state. In many states a special exemption is made for members of the Native American Church (NAC) to use peyote “in bona fide religious ceremonies,” often regardless of race or tribal membership. But in other states, including Arizona, peyote is legal (or tolerated) for any bona fide religious organization, whether the NAC or not. Check with your local authority for up-to-date laws.

What does peyote do?

Peyote commonly produces visions and philosophical or introspective insights. For more on the peyote experience, see Experience.

Can peyote cause psychological trauma?

If you follow the 6Ss of psychedelic use and avoid taking peyote if you have a family history of mental health issues, there appears to be very little chance of long-term psychiatric issues.

Of course, peyote can make you feel crazy in the short term (acute psychosis), especially if you don’t follow the 6Ss, and this is colloquially known as a “bad trip.”

What does peyote look like?

The features that define peyote include:

  • Small, globose shape, often growing in clumps
  • Thick, waxy, green or blue-green skin
  • Uneven ribs of varying number
  • Sticky, yellow-white tufts; no spines
  • Occasional pink or white peyote flower or flowers on top

Where to buy peyote?

Many people find peyote for sale online. While that means that reputable suppliers are just a click away, it’s important to understand that buying it this way could mean supporting illegal or unsustainable harvesting practices—as well as contributing to the peyote shortage among Native Americans who use peyote for religious purposes.

Is peyote legal to grow?

Peyote is legal to grow in many countries even where mescaline is illegal, but this doesn’t include the United States (with some notable exceptions). In many countries, you can buy peyote seeds and living buttons to grow at home. Always check your local laws before cultivating peyote and be aware that, while it’s a relatively low-maintenance cactus to grow, it may take several years to establish a decent-sized garden. If growing peyote from seed, it’ll probably take decades.

The cultivation of Lophophora (Peyote).

This description will tell you how to grow peyote. You should be aware that peyote is one of the slowest growing cacti. Don’t let this put you down, I have found a way  to speed them up a bit.
  In nature they will start flowering after about 10 years, in culture about 5 years and in my way 3 years, some even in the second year.
   The best time to start with seeds is in the early spring.
Get cactus earth from your local flower shop or nursery, try to work a bit clean, although the whole thing is not very sensitive. Put the earth in clean, preferably plastic pots. Make the earth really soaking wet. leave the pots for one day to let the excess of water drip out.
   Now you can put the seeds in. They should be put just under the surface, it is not really necessary  that they are covered with earth. Cover the pot with a piece of transparent  plastic, which can be fixed under the edge with elastic or tape. It seems strange to grow cacti in such an extremely humid atmosphere, but it is o.k.. Put the pots in a sunny place, like behind a window on the south, it is nice if there is a radiator under the window, or if you want to do it more professional, you can use something that keeps the earth temperature around 22C (something like  an electric blanket) Keep the pots covered with the plastic, there is no need to give water for weeks. Within two weeks tiny green balls will appear, the baby peyote’s. After 3/4 weeks from the start, you can start making very small holes in the plastic,  after a few days make some more and later make them bigger. In this way get adapted to the dryer conditions  in this hard, hard world.
  Once there are so many holes, that the humidity is the same as in the surrounding you can take away the plastic (this will be about 8-10 weeks after starting). As long a the cacti are so small, they are quit vulnerable, be careful. Once the top layer of the earth gets dry, you can start watering, but never let them have “wet feet”.
   The first two years, warm earth is good, as long as they grow (Which depends on the climate in which you live).  In about the middle of the autumn stop giving water. To get them well through the winter you have to keep them dry, most trouble, i.e. rot is caused by to much water, remember it is a desert plant, it can stay alive , for a unbelievable long time without water, don’t worry. In winter, you can let the temperature  drop to 4 to 5C.
   When the sun gets stronger in spring they can have water again. You might have to even soak the pots for a while, if the first water just runs through the earth, without holding it. These plants like it hot. I keep them in a greenhouse and never open the  windows, sometimes temperature rises  to even 50 C, I used  to keep them in the summer outdoors, in a upside down aquarium, which worked well . When it is so hot do give enough water, keep them wet. be careful with fertilizers, if you give them fresh earth every two/three years, if you want to use fertilizer, use cacti fertilizer from a local shop, use half of the prescribed amount, if the  the plant gets to much, it will burst, that won’t kill it, but it will take one or two years to overgrow the damage.
   After the first year, it is better to put them in separate pots (if anything happens you can treat them individually). A small pot (5 cm) will do fine, it is best to do this in spring, before you start giving water. Press the earth well around the cacti. Keep the earth a bit below the edge of the pot, to make giving water easier. The green part of the plant should be above the surface, to prevent rot. Bigger plants should also be kept in not to big pots, so that they don’t stay wet for too long a period.
   Another way to grow peyote is by cutting  buttons from a plant. Bigger plants start growing more and more buttons and there is also a kind or a variety, which grows  many buttons. Cut off the button with a real sharp knife and leave the button to form a callus on the wound, this might take a week or two. Then put the button on top of the earth, and it will start growing roots easily (here also warm feet will  speed up the process).
Peyote can be crafted on different other cacti, Trichocereus will do fine. Crafting will speedup growth. Best is to use young, growing buttons and craft them on a also young, growing cacti. Use a  sharp, sterilized knife. The knife can be sterilized with the flame of a lighter. In the cutting of both cacti, you will see a ring, it would be perfect if the rings are the same size, which usually is not the case. The plant transports food and water through this ring, so the rings have to touch each other, so that the top can get what it needs. To make sure, that there will be a connection the top is placed out of center with the base, then there will always be two connection points. When the top is placed, it needs a little pressure, this can be done with elastic or plastic foil, which can be connected on the needles of the base cacti.

Because it’s an endangered species, growing peyote at home—whether from cuttings or peyote cactus seeds—could help to save it from extinction. In fact, wild peyote should never be picked from unless by licensed peyoteros for use in Native ceremonies.

How long does peyote last in storage?

Peyote buttons appear to retain mescaline for an exceptionally long time—potentially even thousands of years. The key (once thoroughly dried) is proper storage in cool, dark, dry conditions, ideally in an airtight container.

How do you take peyote?

Peyote buttons can be eaten whole or brewed as peyote tea. A moderate dose of 200-400 mg mescaline can be achieved by ingesting around six buttons.

Can you smoke peyote?

Smoking peyote is generally ineffective. And smoking extracted mescaline salts isn’t recommended either.

What is pomada de peyote?

Pomada de peyote in English basically means “peyote gel.” This Mexican peyote cream or ointment, which also contains marijuana, is sold as a remedy for aches and pains, cramps, coughs, angina, and other conditions. Although part of an eons-old tradition of medicinal use, it appears to be a relatively new preparation of peyote cactus for sale in Mexico. In 2016, U.S. Customs and Border Protection issued a reminder of its Schedule I status.

Can I microdose with peyote?

Peyote can be microdosed by ingesting around half a button (20-40 mg mescaline) every four days or so. In fact, this may be one of its traditional uses; the Tarahumara Indians are said to consume small amounts of the cactus to combat hunger and fatigue while hunting. In general, though, and certainly to avoid nausea, it may be preferable to microdose pure mescaline (and, given the endangered status of peyote, San Pedro may be a preferable source).

What is peyote’s mescaline content compared to San Pedro and Peruvian torch?

Peyote’s mescaline content is typically 1-6% by dry weight, tending toward the low-middle part of this range. The mescaline content of San Pedro (T. pachanoi) and Peruvian torch (T. peruvianus) is less in general. But in both cacti it tends to be highly variable. In San Pedro, mescaline content is said to range between 0.025% and 2.375% by dry weight, and Peruvian torch has been found to contain up to 0.817% mescaline by dry weight and sometimes none at all.

What’s peyote’s tolerance effect?

Peyote generally produces a tolerance that lasts several days, and it also produces cross-tolerance to other psychedelics like LSD and psilocybin. The potency of each will likely be diminished for a little while after taking peyote. It’s therefore recommended to wait several days between doses of any of these substances.

Can I mix it with other drugs?

Lophophora williamsii (peyote) should never be mixed with tramadol, as it can lead to serotonin syndrome. Also avoid mixing peyote with alcohol, cannabis, amphetamines or cocaine. Click here for a detailed chart of safe drug combinations.


We recommend starting at the medium experience level if you have not tried them before, as the visuals can be quite intense and harder to handle for inexperienced users. Set and setting are extremely important for a positive experience. We also highly encourage people to have a guide or sitter if they are new to psychedelics.

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5 reviews for Buy Lophophora Williamsii (Peyote)

  1. Elad

    I purchased this item a few years ago and received it in very good health and size I was excited that it was about to flower for me and unfortunately I had to move during winter and it was hurt very badly and couldn’t be brought back from the shock of temperature change or at least I believe that is what happened because shortly after moving it just went soft to mush and finally rotted I did not eat the cacti for the look itself was a deadly looking orange yellow soup that smelled awful I could not bring myself to eat it even after drying it out I just love to grow the cacti but am disappointed my larger specimen died due to how long they take just to come into maturity and flower. It was definitely not in any way avalons fault as I said it was very healthy and happy when it arrived.

  2. Aristique

    it is very very good and enough for the awesome experience.

  3. francise

    wow old days. I have bought a peyote plant for my cactus collection from Holland in 2001
    it is now about 100 -103 cm diameter size on my garden In the summers amazing flowers on

  4. Sarah

    Came in stealthed in a save package so nothing could happen while deliveres grows like it should 5/5

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